Cell-cycle inhibition by Helicobacter pylori L-asparaginase.

Helicobacter pylori (H.pylori) is a major human pathogen causing chronic gastritis, peptic ulcer, gastric cancer, and mucosa-associated lymphoid tissue lymphoma.One of the mechanisms whereby it induces damage depends on its interference with proliferation of host tissues.We here describe the discovery of a novel bacterial factor able to inhibit the

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Mechanistic and therapeutic distinctions between cardiosphere-derived cell and mesenchymal stem cell extracellular vesicle non-coding RNA

Abstract Cell therapy limits ischemic injury following myocardial infarction (MI) by preventing cell death, modulating the immune response, and promoting tissue regeneration.The therapeutic efficacy of cardiosphere-derived cells (CDCs) and mesenchymal stem cells (MSCs) is associated with extracellular vesicle (EV) release.Prior head-to-head compari

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